hemophilia B
MeSH: D002836ORPHA: 988793 Treatments Available
Overview
inherited blood coagulation disease that has material basis in Factor IX deficiency, which makes coagulation much more prolonged. The disease is inherited as an X-linked recessive trait
Available Treatments (3)
| Drug | Form | Status | Countries | Lead Time |
|---|---|---|---|---|
| fitusiran Orphan Cold Chain | Injection, subcutaneous | FDA Approved | 1 | — |
| fidanacogene elaparvovec Orphan Cold Chain | — | FDA Approved (2024) | 1 | — |
| marstacimab Orphan Cold Chain | — | FDA Approved (2024) | 1 | — |
Clinical Presentation
Signs and symptoms associated with hemophilia B, sourced from HPO and Orphanet clinical annotations.
HematuriaPoor wound healingIntracranial hemorrhageProlonged bleeding timeProlonged partial thromboplastin timeSpontaneous, recurrent epistaxisProlonged bleeding after surgeryJoint hemorrhageProlonged bleeding after dental extractionReduced factor IX activityIntramuscular hematomaCephalohematomaDelayed onset bleedingMenometrorrhagia
Classification & Codes
MeSH Code
D002836Orphanet Code
ORPHA:98879hemophilia B
| MeSH | D002836 |
| Orphanet | ORPHA:98879 |
| Treatments | 3 drug(s) |
| Symptoms on record | 14 signs |
| Status | published |
Treatment Summary
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO