Ambrisentan

Orphan DrugFDA Approved

Description

Ambrisentan is a selective endothelin type A receptor antagonist indicated for pulmonary arterial hypertension. It improves exercise capacity and delays clinical worsening in PAH patients. It has a more favorable hepatotoxicity profile compared to non-selective endothelin receptor antagonists.

Indications & Therapeutic Use

pulmonary arterial hypertension, WHO Group 1 pulmonary hypertension

Linked Diseases:

Global Availability (7 countries)

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Available Through

This drug is available for procurement through the following fulfilment partner.

Fulfilment Partner
Ambrisentan
Generic Nameambrisentan
Brands1 brand available
Active Ingredientambrisentan
Drug Classpulmonary arterial hypertension
ManufacturerGilead Sciences
Dosage Formsoral tablet 5mg, 10mg
Medical CodeC02KX02
Orphan StatusYes — Orphan Drug
Cold ChainNot Required
Lead Time10 days
Reg. StatusFDA Approved
Clinical TrialNCT00091559
Countries7 countries
Authority Signals
Last Verified3/21/2026
Data ConfidenceHigh (AI + Pharmacist)
Source Citations8 Validated Nodes