Ravulizumab

Orphan Drug Cold Chain RequiredFDA Approved

Description

Ravulizumab is a long-acting C5 complement inhibitor used across multiple rare complement-mediated disorders, including paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome. It is a major specialty biologic because of its extended dosing interval and broad orphan footprint across hematology, nephrology, and neurology. The product is widely tracked in global access discussions due to its high-cost biologic profile and infusion-center requirements.

Indications & Therapeutic Use

paroxysmal nocturnal hemoglobinuria, atypical hemolytic uremic syndrome, generalized myasthenia gravis, neuromyelitis optica spectrum disorder

Global Availability (5 countries)

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Available Through

This drug is available for procurement through the following fulfilment partner.

Fulfilment Partner
Ravulizumab
Generic Nameravulizumab
Brands1 brand available
Active Ingredientravulizumab
Drug Classparoxysmal nocturnal hemoglobinuria
ManufacturerAlexion Pharmaceuticals
Dosage FormsConcentrate for solution for infusion
Medical CodeL04AJ
Orphan StatusYes — Orphan Drug
Cold ChainRequired
Reg. StatusFDA Approved
Clinical TrialNCT04119050
Countries5 countries
Authority Signals
Last Verified7/24/2026
Data ConfidenceHigh (AI + Pharmacist)
Source Citations6 Validated Nodes