Rituximab

Orphan Drug Cold Chain RequiredFDA Approved

Description

Rituximab is a chimeric monoclonal antibody targeting CD20-positive B cells, approved for various hematologic malignancies and autoimmune conditions. It has been used off-label in steroid-resistant nephrotic syndrome type 1 (congenital nephrotic syndrome) and shows promise in certain cases of treatment-resistant disease. The drug depletes B lymphocytes, reducing antibody-mediated kidney damage.

Indications & Therapeutic Use

non-Hodgkin lymphoma, chronic lymphocytic leukemia, rheumatoid arthritis, steroid-resistant nephrotic syndrome

Global Availability (11 countries)

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Available Through

This drug is available for procurement through the following fulfilment partner.

Fulfilment Partner
Rituximab
Generic Namerituximab
Brands1 brand available
Active Ingredientrituximab
Drug Classnon-Hodgkin lymphoma
ManufacturerGenentech/Roche
Dosage FormsIV infusion 10mg/mL (100mg/10mL, 500mg/50mL vials)
Medical CodeL01FA01
Orphan StatusYes — Orphan Drug
Cold ChainRequired
Lead Time14 days
Reg. StatusFDA Approved
Clinical TrialNCT00498368
Countries11 countries
Authority Signals
Last Verified3/21/2026
Data ConfidenceHigh (AI + Pharmacist)
Source Citations12 Validated Nodes