Trabectedin

Orphan Drug Cold Chain RequiredFDA Approved

Description

Trabectedin is a marine-derived antineoplastic agent approved for treatment of advanced soft tissue sarcomas including liposarcoma and leiomyosarcoma. It binds to the minor groove of DNA, interfering with transcription and DNA repair mechanisms. The drug has shown particular efficacy in myxoid liposarcoma and dedifferentiated liposarcoma subtypes.

Indications & Therapeutic Use

advanced soft tissue sarcoma, liposarcoma, leiomyosarcoma, relapsed ovarian cancer

Global Availability (8 countries)

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Available Through

This drug is available for procurement through the following fulfilment partner.

Fulfilment Partner
Trabectedin
Generic Nametrabectedin
Brands1 brand available
Active Ingredienttrabectedin
Drug Classadvanced soft tissue sarcoma
ManufacturerJanssen/PharmaMar
Dosage FormsIV infusion 0.25mg/mL, 1mg/mL (1mg/4mL, 1mg/20mL vials)
Medical CodeL01CX01
Orphan StatusYes — Orphan Drug
Cold ChainRequired
Lead Time21 days
Reg. StatusFDA Approved
Clinical TrialNCT00061984
Countries8 countries
Authority Signals
Last Verified3/21/2026
Data ConfidenceHigh (AI + Pharmacist)
Source Citations9 Validated Nodes