Trametinib

Orphan DrugFDA Approved

Description

Trametinib is a kinase inhibitor indicated, in combination with dabrafenib, for the treatment of anaplastic thyroid cancer with BRAF V600E mutation. It inhibits MEK1 and MEK2 kinases, which are involved in cell signaling and growth.

Indications & Therapeutic Use

Anaplastic thyroid cancer with BRAF V600E mutation

Linked Diseases:

Global Availability (2 countries)

CountryAccess RouteRegulatory PathwayLead TimeStatus

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Available Through

This drug is available for procurement through the following fulfilment partner.

Fulfilment Partner
Trametinib
Generic NameTrametinib
Brands1 brand available
Active IngredientTrametinib dimethyl sulfoxide
Drug ClassAnaplastic thyroid cancer with BRAF V600E mutation
ManufacturerNovartis
Dosage FormsTablet
Medical CodeL01EE07
Orphan StatusYes — Orphan Drug
Cold ChainNot Required
Reg. StatusFDA Approved
Countries2 countries
Authority Signals
Last Verified3/21/2026
Data ConfidenceHigh (AI + Pharmacist)
Source Citations3 Validated Nodes